Description
Product Characteristics: Duo antibody, FLJ16443 antibody, HAPIP antibody, Huntingtin associated protein interacting protein (duo) antibody, Huntingtin-associated protein-interacting protein antibody, Kalirin (isoform 2) antibody, Kalirin antibody, KALRN antibody, KALRN_HUMAN antibody, Protein Duo antibody, RhoGEF kinase antibody, Serine/threonine kinase with Dbl and pleckstrin homology domains antibody, Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain antibody, TRAD antibody
Target Information: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]